This section is intended for patients prescribed Ninlaro. If you are a member of the public click here. If you are a UK healthcare professional click here.

Before starting treatment with NR d*

* NINLARO (ixazomib), REVLIMID (lenalidomide) and dexamethasone

Although they will know your medical history, there are some important facts your doctor or nurse should be aware of before you start treatment with NRd.

Before you start taking Ninlaro, tell your doctor or nurse if:

You are allergic to ixazomib or to any of the other ingredients in the capsules. The other ingredients in Ninlaro are:

  • Microcrystalline cellulose, magnesium stearate, talc, shellac, propylene glycol, potassium hydroxide, black iron oxide (E172), gelatin and titanium dioxide (E171)
  • Ninlaro 4 mg hard capsules also contain: yellow iron oxide (E172) and red iron oxide (E172)
  • Ninlaro 2.3 mg hard capsules also contain: red iron oxide (E172)

You are taking, have recently taken or might take any other medicines - this includes any over-the-counter medicines that do not need a prescription, vitamins and herbal remedies. In particular, tell your doctor, pharmacist or nurse if you are taking carbamazepine, phenytoin, rifampicin or St. John's wort ( hypericum perforatum) as these can affect the way Ninlaro works

You are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby as Ninlaro is not recommended during pregnancy and/or breast-feeding

You have a history of swelling

You have a history of bleeding

You have a persistent rash

You have persistent nausea, vomiting or diarrhoea

You have or have had liver or kidney problems

You have a history of nerve problems, including tingling and numbness

You need to drive or operate machines, as Ninlaro may cause dizziness

Please also refer to the Revlimid and dexamethasone Patient Information Leaflets before starting NRd

Your doctor or nurse will also do a blood test to check your number of blood cells, before starting treatment.


Do not try to treat your symptoms with any other treatments, or take any over-the-counter drug or herbal supplement, before speaking to your myeloma doctor, pharmacist or nurse.

Your Guide to Treatment with the NRd Regimen

Takeda Oncology has developed a practical guide for patients who have been prescribed NRd. It explains how NRd works, how to take it and possible side effects you may experience

My Treatment Calendar

Takeda Oncology has developed a practical treatment calendar for patients who have been prescribed NRd